Common Penetration Enhancement Techniques3

Electrically Assisted Techniques
Ionotophoresis
Electroporation
Sonophoresis, photophoresis (ultrasound)

SC Bypassed or Removed
Microneedle array
Stratum corneum ablation (chemical peels, microdermabrasion, microscission, laser, etc.)

Vesicles and Particles
Liposomes and analogs (transferosomes,ethosomes, niosomes, etc.)
High velocity particles (PowderJect, Intraject, etc.)

Stratum Corneum Modification
Hydration
Chemical penetration enhancers (see Table 1)