Figure 2. Collagen type I visualization in human skin explants a) without or b) with topical application of the active ingredient at 0.5%; immunostaining—green fluorescence, 40 × magnification

In the present study, clear stimulation of collagen type I synthesis was observed in the aged skin explants topically treated with 0.5% of the active ingredient, compared with untreated explants at D6 and D11 (see Figure 2 and Table 3).