Table 3. The effects of NATAH on both TG and LOXL-1

The data presented indicates that in normal human skin fibroblasts, NATAH, at the concentration of 12 x 10-6 M/L, increases fibulin-5 synthesis by 59% (p < 0.01) and decorin synthesis by 68% (p < 0.01). These figures compare well with those obtained with TGF- β1 (55%, p < 0.01), the usual positive control.