Figure 2. N-Acetyl-Tyr-Arg-O-Hexadecyl Ester (NATAH)

The authors investigated the potential bioactivity of the natural dipeptide Kyotorphin (Tyr-Arg), albeit modified to N-Acetyl-Tyr-Arg-O-Hexadecyl Ester (NATAH) for reasons of topical application and improved bioavailability.