Table 3. F-D data generated by contact mode AFM of mature vs. immature corneocytes

To demonstrate the utility of the method, F-D curves were generated from five mature and five immature corneocytes. The data here shows that the immature corneocytes had a higher adhesive energy (21,612 Joules x10-18) than the mature corneocytes (3,331 Joules x10-18).