Figure 2. The effects of phytosphingosine on the formation of key factors involved in SC formation

Relative expression of involucrin (gray bars), transglutaminase-1 (dark gray bars) and filaggrin (black bars) in keratinocytes after stimulation with 5 µM phytosphingosine, compared with untreated time-matched controls. Loricrin is shown on a different scale in the inset graph (gray hashed bars).