Figure 4. Extent of delivery of the parent compounds and metabolites

Extent of delivery of the parent compounds and metabolites through the skin (culture medium) in both frozen and fresh viable skin for the three model substrates at 200 nmoles; data is expressed as a percentage of the applied dose of radioactivity; log Ko/w of 7-EC, testosterone and BaP is 1.3; 3.3 and 6.5, respectively.